Pfizer
United States - California - San Diego
+ 6 other locations
Pfizer Commercial Oncology is introducing the world to the next era of cancer care. With a growing portfolio of novel therapies, industry-leading R&D, and a goal of delivering eight breakthroughs by 2030 across major cancer types, we're translating cutting-edge science into market-shaping impact. Here, you'll partner with exceptional colleagues across scientific, medical, and manufacturing teams, backed by advanced digital and AI-enabled infrastructure and the authority to accelerate medicines from discovery to delivery. Guided by our values of courage, excellence, equity, and joy, you'll have the opportunity to stretch your skills and build a career that evolves with you—across teams, roles, and the Pfizer enterprise. Join us to make history — for patients, for their families, for the future.
The US Precision Medicine Thoracic Franchise is entering its most consequential — and most complex — growth chapter. Our in-line thoracic portfolio spans two biomarker-defined populations: LORBRENA (lorlatinib) for adults with ALK-positive metastatic non-small cell lung cancer (NSCLC), and the BRAFTOVI + MEKTOVI (encorafenib + binimetinib) regimen for BRAF V600E-mutant metastatic NSCLC. Both sit inside a molecularly driven treatment landscape where the right patient is identified by a biomarker signature. Winning here means mastering precision targeting: reaching narrow, high-value, genomically defined patient populations through the exact clinicians who test for and treat them.
This is a people-management leadership role that demands a strong enterprise leader — one fluent in both commercial strategy and AI-enabled execution, and able to think and operate at the enterprise level. The colleague who leads this team will set a multi-year strategic vision, make thoughtful trade-off and resource-prioritization decisions across two brands, and influence senior leadership across the wider organization. They will operate in an AI-enabled commercial environment where machine-learning-driven customer identification, next-best-action engines, and predictive analytics reshape how, when, and to whom we deliver our message. This person will be required to leverage deep US commercial marketing experience and precision-targeting expertise to lead a highly talented team, connect targeted precision engagement activity directly to outcomes, and elevate what we are able to say — and prove — to our customers in a data-rich, AI-enabled world.
The LORBRENA/BRAF Lung Team Lead reports directly to the Franchise Lead, Precision Medicine Thoracic Franchise, and owns the continued growth of LORBRENA (including CROWN lifecycle execution) and the BRAFTOVI + MEKTOVI BRAF V600E-mutant NSCLC (lung) indication. This role requires close cross-functional coordination with the BRAFTOVI/MEKTOVI brand team to align lung-specific strategy, promotional assets, and field execution while preserving one coherent brand voice. The role requires strong leadership, collaboration, communication and decision-making skills, change agility, and a proven track record working across the broader franchise team, CMO, Medical, Market Access, Sales, Insights & Analytics, AI/Data Science partners, and agency cohorts.
Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact.
Last Date to Apply for Job: September 29th, 2026
Additional Location Information: New York, NY; Collegeville, PA; Cambridge, MA; Groton, CT; Bothell, WA, Lake Forest, IL; La Jolla, CA
Eligible for Relocation Package: No
#LI-PFE
The annual base salary for this position ranges from $230,900.00 to $384,800.00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 25.0% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site – U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.
This role is posted in multiple locations. If you are applying for the role in an secondary job posting location where pay transparency regulations apply, your Talent Advisor will share the local pay information with you during the first interview.
Relocation assistance may be available based on business needs and/or eligibility.
Candidates must be authorized to be employed in the U.S. by any employer.
U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future.
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Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.
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